Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 19/20 | 0.47 |
| ▸ | USP2 | O75604 | 11/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282158 | 0.89 | CYP2D6 (0.46) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL27281828 | 0.85 | CYP3A4 (0.55) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL13400770 | 0.85 | CYP3A4 (0.55) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL13400806 | 0.83 | CYP3A4 (0.54) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL18926696 | 0.81 | CYP3A4 (0.56) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL17828066 | 0.81 | PIK3CD (0.38) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL27281826 | 0.80 | CYP3A4 (0.48) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL18595844 | 0.79 | TSHR (0.41) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL27281806 | 0.79 | CYP2D6 (0.35) | CYP3A4USP2TSHRCYP2C19CYP2C9 | |
| SCHEMBL22544529 | 0.77 | CYP3A4 (0.51) | CYP3A4USP2TSHRCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |