Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 9/20 | 0.47 |
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.47 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27272956 | 1.00 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL27275434 | 1.00 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL27279001 | 1.00 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL27276235 | 1.00 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL27281880 | 0.93 | TOP1 (0.43) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL26374814 | 0.87 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL6257041 | 0.85 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL30644155 | 0.85 | HRAS (0.47) | HRASESR1ESR2TOP1POLB | |
| Hydrochloric Acid SCHEMBL6178124 | 0.85 | TOP1 (0.55) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL1844965 | 0.84 | HDAC1 (0.51) | HRASESR1ESR2TOP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1018825-B | Process for preparing poly-4-aminopyrrole-2-carboxamido derivatives | ERBA FARMITALIA (IT) | 1992-10-28 | — | — | CN | disclosed |