Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282922 | 0.89 | DRD1 (0.35) | DRD1PRKCQARPLA2G7SLC22A12 | |
| SCHEMBL30750214 | 0.89 | DRD1 (0.35) | DRD1PRKCQARPLA2G7SLC22A12 | |
| SCHEMBL27266385 | 0.89 | DRD1 (0.35) | DRD1PRKCQARPLA2G7SLC22A12 | |
| SCHEMBL30285720 | 0.87 | DRD1 (0.34) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL27268704 | 0.87 | DRD1 (0.34) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL29237494 | 0.87 | DRD1 (0.34) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL30805149 | 0.87 | DRD1 (0.34) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL30749821 | 0.86 | PRKCQ (0.35) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL27266137 | 0.86 | PRKCQ (0.35) | DRD1PRKCQPLA2G7SLC22A12RHEB | |
| SCHEMBL27266156 | 0.86 | DRD1 (0.36) | DRD1PRKCQARSLC22A12RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |