Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 7/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30930659 | 1.00 | CRBN (0.56) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL27284950 | 0.88 | CRBN (0.56) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL27389389 | 0.82 | CRBN (0.59) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL27388058 | 0.81 | CRBN (0.54) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL23423465 | 0.79 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL30032311 | 0.79 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL29927246 | 0.79 | CRBN (0.61) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL19451301 | 0.79 | CRBN (0.61) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL19451297 | 0.79 | CRBN (0.61) | CRBNIKZF2IKZF3IKZF1DDB1 | |
| SCHEMBL25650407 | 0.79 | CRBN (0.61) | CRBNIKZF2IKZF3IKZF1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024096753-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |