SCHEMBL27286458

SCHEMBL27286458

O=CC1CNCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL519002 0.78
SCHEMBL836049 0.78
SCHEMBL433965 0.78
SCHEMBL6634396 0.76
SCHEMBL294999 0.76
SCHEMBL3850756 0.76
SCHEMBL6020803 0.74
Hydrochloric Acid SCHEMBL27662846 0.74
SCHEMBL27908535 0.74
Hydrochloric Acid SCHEMBL27649807 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104910148-B Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes 西格诺药品有限公司 2017-06-27 CN claimed
CN-104910148-A Aminotriazolopyridines and use thereof as kinase inhibitors SIGNAL PHARM LLC 2015-09-16 CN claimed
CN-101977908-B (pyrazolyl carbonyl) imidazolidinone derivatives for the treatment of retroviral diseases AICURIS GMBH & CO KG 2014-04-23 CN claimed
CN-103214422-A Preparation methods and anti-cancer effect of novel substituted amido imidazolone derivatives UNIV NANTONG 2013-07-24 CN claimed
CN-102203093-A Aminotriazolopyridines and their use as kinase inhibitors SIGNAL PHARM LLC 2011-09-28 CN claimed
CN-101977908-A (pyrazolyl carbonyl) imidazolidinone derivatives for the treatment of retroviral diseases AICURIS GMBH & CO KG 2011-02-16 CN claimed
CN-101379056-A Compounds for the inhibition of integrins and use thereof JERINI AG (DE) 2009-03-04 CN claimed
CN-1480451-A Photoactive compound used as intermediate for preparing photoactive 2-imidazoline-5-ketone or 2-imdazoline-5-thio-ketone derivative ����-���ʿ�ũҵ��ѧ��˾ 2004-03-10 CN claimed
CN-1129583-C Compounds useful as intermediates in the preparation of optically active 2-imidazolin-5-one or 2-imidazolin-5-thione derivatives RHONE POULENC AGROCHIMIE (FR) 2003-12-03 CN claimed
CN-1265394-A Compounds useful as intermediates in the preparation of optically active 2-imidazolin-5-one or 2-imidazolin-5-thione derivatives RHONE POULENC AGROCHIMIE (FR) 2000-09-06 CN claimed
CN-1055465-C Optically active 2-imidazoline-5-ketone derivative and preparation method and application thereof RHONE POULENC AGROCHIMIE (FR) 2000-08-16 CN claimed
CN-1111240-A 2-alkoxy-2-imidazolin-5-one fungicide derivative RHONE POULENC SA (FR) 1995-11-08 CN claimed
CN-1111241-A Derivative of 2-imidazolin-5-one fungicide RHONE POULENC AGROCHIMIE (FR) 1995-11-08 CN claimed
CN-1106803-A Fungicidal optically active 2-imidazolin-5-one and 2-imidazolin-5-thione derivatives RHONE POULENC AGROCHIMIE (FR) 1995-08-16 CN claimed
CN-107216315-B Flavone imidazole compound and preparation method thereof 盐城师范学院 2020-03-17 CN disclosed
CN-110506039-A Compounds and methods for targeted degradation of androgen receptor ARVINAS INC 2019-11-26 CN disclosed
CN-105530932-B Primary formamide as BTK inhibitor 艾伯维公司 2019-09-27 CN disclosed
CN-1074215-A Mycocidal 2-tetrahydroglyoxaline-5-ketone and 2-tetrahydroglyoxaline-5-40 thione derivatives RHONE POULENC AGROCHIMIE (FR) 1993-07-14 CN disclosed
CN-1069728-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1993-03-10 CN disclosed
CN-1031530-A Benzenesulfonyl carboxamide compound, intermediate AMERICAN CYANAMID CO (US) 1989-03-08 CN disclosed