Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CETP | P11597 | 1/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798415 | 1.00 | SPHK1 (0.59) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL2727038 | 1.00 | SPHK1 (0.59) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL2728416 | 1.00 | SPHK1 (0.59) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL669995 | 0.91 | CYP2D6 (0.50) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL27544781 | 0.90 | HTT (0.53) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL898772 | 0.87 | TRPV1 (0.49) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL14880189 | 0.83 | SPHK1 (0.61) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL9117099 | 0.83 | SPHK1 (0.61) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL26641779 | 0.81 | CYP2D6 (0.63) | SPHK1CYP2D6HTTCYP1A2CYP3A4 | |
| SCHEMBL11302893 | 0.81 | SPHK1 (0.58) | SPHK1CYP2D6HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632425-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE, AN ANIONIC SURFACTANT AND A NONIONIC, AMPHOTERIC OR ZWITTERIONIC SURFACTANT | L'Oréal (FR) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012055809-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE, AN ANIONIC SURFACTANT AND A NONIONIC, AMPHOTERIC OR ZWITTERIONIC SURFACTANT | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |