Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.42 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22566223 | 0.86 | CRBN (0.49) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL24480802 | 0.80 | CRBN (0.47) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL16223943 | 0.80 | CRBN (0.58) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL21897792 | 0.78 | CRBN (0.46) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL22661451 | 0.78 | CRBN (0.44) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL25899657 | 0.78 | CRBN (0.44) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL18885279 | 0.78 | CRBN (0.44) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL25899593 | 0.78 | CRBN (0.44) | CRBNDDB1IKZF3IKZF1BRD4 | |
| SCHEMBL20323937 | 0.76 | CRBN (0.45) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL24294674 | 0.76 | CRBN (0.45) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |