Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.53 |
| ▸ | JAK1 | P23458 | 7/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923301 | 1.00 | TYK2 (0.53) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL27293787 | 0.92 | TYK2 (0.53) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923102 | 0.92 | TYK2 (0.53) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27290121 | 0.90 | TYK2 (0.57) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL27290768 | 0.90 | TYK2 (0.67) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923199 | 0.90 | TYK2 (0.51) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27293829 | 0.90 | TYK2 (0.51) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923163 | 0.89 | TYK2 (0.53) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27290116 | 0.89 | TYK2 (0.53) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27290258 | 0.88 | TYK2 (0.51) | TYK2JAK1KCNH2JAK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |