Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27283744 | 0.85 | DDB1 (0.40) | ELANEDDB1CRBNPDE4BPDE4D | |
| SCHEMBL8589216 | 0.85 | ELANE (0.42) | ELANEDDB1CRBNNAPRTPDE4B | |
| SCHEMBL28174800 | 0.79 | FEN1 (0.48) | NAPRTPDE4AKCNH2TNKS | |
| SCHEMBL4701899 | 0.79 | KDM4E (0.45) | DDB1CRBN | |
| SCHEMBL9109277 | 0.79 | PIK3CA (0.34) | TOP2ATOP2B | |
| SCHEMBL16344498 | 0.73 | PDE4B (0.44) | ELANEDDB1CRBNPDE4BPDE4D | |
| SCHEMBL30585961 | 0.72 | KDM4E (0.40) | HTR3APDE4BPDE4DPDE4A | |
| SCHEMBL7960307 | 0.71 | KDM4E (0.55) | PDE4AKCNH2TOP2ATOP2B | |
| SCHEMBL9287324 | 0.71 | PDE4B (0.44) | PDE4BPDE4D | |
| SCHEMBL16344276 | 0.70 | PDE4B (0.47) | ELANEDDB1CRBNPDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036005-C | Pharmaceutical composition containing 7-bicyclic substituted-3-quinolone carboxylic acid derivative and process for preparing same | BAYER AG (DE) | 1997-10-01 | — | — | CN | disclosed |
| CN-1097759-A | Process for preparing pharmaceutical composition containing 1-bicyclic substituted-3-quinolone carboxylic acid derivative | BAYER AG (DE) | 1995-01-25 | — | — | CN | disclosed |
| CN-1027165-C | Process for preparing 7-ring substituted-3-quinolone carboxylic acid derivatives | BAYER AG (DE) | 1994-12-28 | — | — | CN | disclosed |
| CN-1039589-A | 7- (1-pyrrolidinyl) -3-quinolone-and 1, 5-naphthyridonecarboxylic acid derivatives and process for preparing same | BAYER AG (DE) | 1990-02-14 | — | — | CN | disclosed |