Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.53 |
| ▸ | HRH1 | P35367 | 7/20 | 0.46 |
| ▸ | CCR3 | P51677 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27292808 | 0.89 | CRBN (0.61) | CRBNDDB1POLBCYP19A1 | |
| SCHEMBL31382122 | 0.84 | CRBN (0.50) | CRBNDDB1POLBHTR7 | |
| SCHEMBL30981359 | 0.84 | CRBN (0.49) | CRBNDDB1POLBAR | |
| SCHEMBL27292908 | 0.83 | CRBN (0.56) | CRBNDDB1POLBCYP19A1 | |
| SCHEMBL24671839 | 0.81 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL24670629 | 0.81 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL24671836 | 0.81 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL25506792 | 0.80 | CRBN (0.44) | CRBNDDB1POLBAR | |
| SCHEMBL27292930 | 0.80 | CRBN (0.78) | CRBNDDB1POLBCYP19A1 | |
| SCHEMBL27292838 | 0.79 | CRBN (0.52) | CRBNDDB1POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059808-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024059808-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |