Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732990 | 0.82 | KCNJ1 (0.60) | KCNJ1KCNH2 | |
| SCHEMBL2731889 | 0.82 | KCNH2 (0.55) | KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL2733934 | 0.81 | KCNJ1 (0.58) | KCNJ1KCNH2 | |
| SCHEMBL2733631 | 0.78 | KCNJ1 (0.49) | KCNJ1KCNH2 | |
| SCHEMBL10234057 | 0.77 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2729938 | 0.73 | KCNJ1 (0.46) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL17360760 | 0.71 | KCNJ1 (0.80) | KCNJ1KCNH2 | |
| SCHEMBL14782785 | 0.71 | KCNJ1 (0.85) | KCNJ1KCNH2 | |
| SCHEMBL15210266 | 0.71 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL296919 | 0.70 | KCNJ1 (0.83) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632464-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058134-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |