SCHEMBL27294253

SCHEMBL27294253

Cn1cnnc1-c1ccc(C2CC2)cc1-c1cc(NCCC#N)nc(N2Cc3c(cc(CN4CCC5(CC5)C4)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293655 0.92 CBLB (0.51) CBLB
SCHEMBL27294262 0.92 CBLB (0.51) CBLB
SCHEMBL30956978 0.92 CBLB (0.55) CBLB
SCHEMBL27291110 0.92 CBLB (0.55) CBLB
SCHEMBL27292490 0.91 CBLB (0.54) CBLB
SCHEMBL30956932 0.91 CBLB (0.54) CBLB
SCHEMBL27305574 0.91 CBLB (0.54) CBLB
SCHEMBL27295593 0.89 CBLB (0.57) CBLB
SCHEMBL27293161 0.89 CBLB (0.51) CBLB
SCHEMBL27296212 0.89 CBLB (0.49) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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