SCHEMBL27295398

SCHEMBL27295398

C[C@H]1CCCN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cc(-c4cc(C#N)ccc4-c4nncn4C)cc(NCCC4CC4)n2)C3=O)C1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293827 0.98 CBLB (0.58) CBLB
SCHEMBL27324742 0.97 CBLB (0.55) CBLB
SCHEMBL27296860 0.97 CBLB (0.55) CBLB
SCHEMBL27292812 0.94 CBLB (0.55) CBLB
SCHEMBL27297056 0.94 CBLB (0.58) CBLB
SCHEMBL27297495 0.94 CBLB (0.55) CBLB
SCHEMBL27293572 0.94 CBLB (0.55) CBLB
SCHEMBL27297601 0.94 CBLB (0.55) CBLB
SCHEMBL27293157 0.93 CBLB (0.58) CBLB
SCHEMBL27294665 0.93 CBLB (0.58) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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