SCHEMBL27295656

SCHEMBL27295656

CCOC(=O)c1cccc(/C=C\c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.54
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51
ALDH1A1 P00352 5/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
HPGD P15428 1/20 0.51
XBP1 P17861 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
TTR P02766 2/20 0.50
PTGS2 P35354 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360421 1.00 PPARG (0.54) PPARGCYP4F2CYP4A11CTDSP1ALDH1A1
SCHEMBL11360426 1.00 PPARG (0.54) PPARGCYP4F2CYP4A11CTDSP1ALDH1A1
SCHEMBL5164891 0.88 SMN1; SMN2 (0.61) CYP4F2CYP4A11ALDH1A1MAPTKDM4E
SCHEMBL11237900 0.88 CYP4F2 (0.51) CYP4F2CYP4A11ALDH1A1MAPTKDM4E
SCHEMBL11237903 0.88 CYP4F2 (0.51) CYP4F2CYP4A11ALDH1A1MAPTKDM4E
SCHEMBL9000465 0.87 SMN1; SMN2 (0.50) CYP4F2CYP4A11ALDH1A1KDM4EMEN1
SCHEMBL9000468 0.87 SMN1; SMN2 (0.50) CYP4F2CYP4A11ALDH1A1KDM4EMEN1
SCHEMBL27676757 0.86 CYP4F2 (0.50) CYP4F2CYP4A11ALDH1A1MAPTKDM4E
SCHEMBL4264736 0.85 CA12 (0.63) TTR
SCHEMBL4264739 0.85 CA12 (0.63) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1037141-A The alkylamine derivative that replaces BANYU PHARMA CO LTD (JP) 1989-11-15 CN disclosed