SCHEMBL27296298

SCHEMBL27296298

CCc1cc2c(c(C(F)(F)F)c1)CN(c1cc(-c3cc(C#N)ccc3-c3nncn3C)cc(NCCC#N)n1)C2=O

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27320640 0.95 CBLB (0.52) CBLB
SCHEMBL30956927 0.95 CBLB (0.57) CBLB
SCHEMBL27308801 0.95 CBLB (0.57) CBLB
SCHEMBL27308959 0.94 CBLB (0.57) CBLB
SCHEMBL30956979 0.94 CBLB (0.57) CBLB
SCHEMBL27324998 0.93 CBLB (0.55) CBLB
SCHEMBL27317519 0.93 CBLB (0.55) CBLB
SCHEMBL27295027 0.92 CBLB (0.57) CBLB
SCHEMBL27292965 0.92 CBLB (0.56) CBLB
SCHEMBL27294013 0.92 CBLB (0.55) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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