Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL271240 | 0.99 | HTR2A (0.51) | HTR2AMAPTPARP15PARP10TDP1 | |
| Hexane SCHEMBL6092528 | 0.92 | HTR2A (0.48) | HTR2AMAPTPARP15PARP10TDP1 | |
| Hydrochlorthiazide SCHEMBL8989377 | 0.90 | HTR2A (0.44) | HTR2AMAPTPARP15PARP10TDP1 | |
| SCHEMBL14308527 | 0.82 | PARP15 (0.52) | MAPTPARP15PARP10TDP1RAB9A | |
| SCHEMBL6385223 | 0.80 | HTR2A (0.54) | HTR2AMAPTBCL9CTNNB1RAB9A | |
| SCHEMBL18034381 | 0.79 | MAPT (0.49) | MAPTPARP15PARP10TDP1RAB9A | |
| SCHEMBL7092278 | 0.79 | HTR2A (0.53) | HTR2AMAPTBCL9CTNNB1LMNA | |
| SCHEMBL7174046 | 0.78 | HTR2A (0.53) | HTR2AMAPTBCL9CTNNB1LMNA | |
| SCHEMBL17030382 | 0.78 | BCL9 (0.53) | MAPTPARP15PARP10TDP1BCL9 | |
| SCHEMBL7096139 | 0.78 | HTR2A (0.52) | HTR2AMAPTBCL9CTNNB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116272259-A | Desulfurization and decarbonization solvent suitable for low-pressure gas and application thereof | 四川精事达科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115541762-A | Method for detecting ritonavir starting material 02 related substances | 武汉海特生物创新医药研究有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-112500367-A | Refining method of ritonavir intermediate | 盐城迪赛诺制药有限公司 | 2021-03-16 | — | — | CN | claimed |
| EP-1302468-A1 | Processes and intermediates for manufacturing retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2003-04-16 | — | — | EP | claimed |
| EP-1090914-A2 | Processes and intermediates for manufacturing retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| US-5892052-A | Process for making retroviral protease inhibiting compounds | ABBOTT LABORTORIES (US) | 1999-04-06 | — | — | US | claimed |
| US-5659045-A | AIDS THERAPY | ABBOTT LABORATORIES (US) | 1997-08-19 | — | — | US | claimed |
| US-5565418-A | PREPARING CARBAMATE INTERMEDIATES BY REACTING SUBSTITUTED HYDROXYDIAMINE COMPOUND WITH ONE AMINE PROTECTED WITH ACTIVATED ACYLATING AGENT, DEPROTECTING | ABBOTT LABORATORIES (US) | 1996-10-15 | — | — | US | claimed |
| EP-0727419-A2 | Retroviral protease inhibiting compounds | Abbott Laboratories (US) | 1996-08-21 | — | — | EP | claimed |
| CN-115541762-B | Method for detecting related substances of ritonavir starting material 02 | 武汉海特生物创新医药研究有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-116272259-B | Desulfurization and decarbonization solvent suitable for low-pressure gas and application thereof | 四川精事达科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116272259-A | Desulfurization and decarbonization solvent suitable for low-pressure gas and application thereof | 四川精事达科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115541762-A | Method for detecting ritonavir starting material 02 related substances | 武汉海特生物创新医药研究有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-114709505-A | Method for directly regenerating waste lithium ion battery anode material into flexible current collector-free electrode | 中南大学 | 2022-07-05 | — | — | CN | disclosed |
| WO-1995009614-A1 | PHARMACEUTICAL COMPOSITION | ABBOTT LABORATORIES (US) | 1995-04-13 | — | — | WO | disclosed |
| WO-1995007696-A1 | PHARMACEUTICAL COMPOSITION OF HIV-PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1995-03-23 | — | — | WO | disclosed |
| US-5354866-A | Treating HIV infections | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994019332-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-09-01 | — | — | WO | disclosed |
| WO-1994014436-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-07-07 | — | — | WO | disclosed |
| EP-0486948-A2 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1992-05-27 | — | — | EP | disclosed |