SCHEMBL27297927

SCHEMBL27297927

CC(C#N)CNc1cc(-c2cc(C#N)ccc2-c2nncn2C)cc(N2Cc3c(cc(CN4CCC4)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27298045 1.00 CBLB (0.56) CBLB
SCHEMBL27298133 1.00 CBLB (0.56) CBLB
SCHEMBL27298950 0.93 CBLB (0.56) CBLB
SCHEMBL27293570 0.92 CBLB (0.54) CBLB
SCHEMBL27293729 0.92 CBLB (0.54) CBLB
SCHEMBL27300523 0.91 CBLB (0.54) CBLB
SCHEMBL27299713 0.91 CBLB (0.54) CBLB
SCHEMBL27297923 0.91 CBLB (0.54) CBLB
SCHEMBL27295027 0.90 CBLB (0.57) CBLB
SCHEMBL27299451 0.90 CBLB (0.58) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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