SCHEMBL27298613

SCHEMBL27298613

CC(C)CNc1cc(-c2cc(C#N)ccc2-c2nncn2C)cc(N2Cc3c(cc(CN4CC5(CCCC5)C4)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27290085 0.94 CBLB (0.55) CBLB
SCHEMBL27298948 0.94 CBLB (0.53) CBLB
SCHEMBL27298947 0.93 CBLB (0.53) CBLB
SCHEMBL27298335 0.93 CBLB (0.56) CBLB
SCHEMBL27298883 0.93 CBLB (0.53) CBLB
SCHEMBL27299451 0.92 CBLB (0.58) CBLB
SCHEMBL27298950 0.92 CBLB (0.56) CBLB
SCHEMBL27298611 0.91 CBLB (0.54) CBLB
SCHEMBL27299599 0.90 CBLB (0.55) CBLB
SCHEMBL27299598 0.90 CBLB (0.55) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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