Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29834698 | 0.87 | ACACB (0.37) | BTKACACBLRRK2HRH3TGFBR1 | |
| SCHEMBL29834626 | 0.79 | KDR (0.42) | ACACB | |
| SCHEMBL27299248 | 0.78 | ACACB (0.34) | ACACBLRRK2SLC6A4 | |
| SCHEMBL27312865 | 0.77 | HRH3 (0.38) | ACACBHRH3 | |
| SCHEMBL27299379 | 0.72 | LRRK2 (0.43) | LRRK2KCNH2 | |
| SCHEMBL27300805 | 0.71 | LRRK2 (0.34) | ACACBLRRK2HRH3TGFBR1KCNH2 | |
| SCHEMBL27299255 | 0.71 | LRRK2 (0.44) | LRRK2TGFBR1 | |
| SCHEMBL27312862 | 0.70 | LRRK2 (0.41) | LRRK2TGFBR1 | |
| SCHEMBL27299230 | 0.70 | KDR (0.33) | ACACBLRRK2HRH3 | |
| SCHEMBL25430473 | 0.70 | USP30 (0.52) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |