SCHEMBL27299772

SCHEMBL27299772

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c6ccccc6n(-c6ccccc6)c45)n3)c(-n3c4ccccc4c4c(-c5cccc6c5c5ccccc5n6-c5ccccc5)cccc43)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC4 P56524 1/20 0.32
PDE6D O43924 1/20 0.31
DUSP3 P51452 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PDE10A Q9Y233 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27295611 0.95 KDM4E (0.39) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27296542 0.95 KDM4E (0.39) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27296617 0.93 KDM4E (0.37) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27295631 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27295618 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PDE6D
SCHEMBL27316130 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27295843 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27295662 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27296611 0.92 KDM4E (0.36) KDM4EATML3MBTL1HDAC4RXFP1
SCHEMBL27299811 0.91 KDM4E (0.37) KDM4EATML3MBTL1HDAC4PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014932-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DIODE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-01-18 WO disclosed