SCHEMBL27301774

SCHEMBL27301774

Cc1ccc(-c2nncn2C)c(-c2cc(NCC3(CC#N)CC3)nc(N3Cc4c(cc(CN5CCC6(CCC6)C5)cc4C(F)(F)F)C3=O)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293249 0.92 CBLB (0.55) CBLB
SCHEMBL27297278 0.92 CBLB (0.51) CBLB
SCHEMBL27304387 0.92 CBLB (0.47) CBLB
SCHEMBL27301654 0.91 CBLB (0.49) CBLB
SCHEMBL27296646 0.90 CBLB (0.48) CBLB
SCHEMBL27301444 0.89 CBLB (0.47) CBLB
SCHEMBL30956930 0.89 CBLB (0.50) CBLB
SCHEMBL27301773 0.89 CBLB (0.50) CBLB
SCHEMBL27299554 0.87 CBLB (0.55) CBLB
SCHEMBL27303982 0.86 CBLB (0.55) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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