Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508948 | 1.00 | KMT2A (0.50) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL27299978 | 1.00 | KMT2A (0.50) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL27328016 | 1.00 | KMT2A (0.50) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL27306208 | 1.00 | KMT2A (0.50) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL27312247 | 0.99 | KMT2A (0.49) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL27311093 | 0.99 | KMT2A (0.49) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL30172 | 0.99 | KMT2A (0.51) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL7910394 | 0.99 | KMT2A (0.51) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL7908294 | 0.95 | KMT2A (0.52) | KMT2AMAPTHTTMEN1IDH1 | |
| SCHEMBL7908296 | 0.95 | KMT2A (0.52) | KMT2AMAPTHTTMEN1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037334-A | Pyridine derivate | MERCK PATENT GMBH (DE) | 1989-11-22 | — | — | CN | disclosed |