SCHEMBL2730775

SCHEMBL2730775

[CH2]CC[SiH2]C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6299060 0.80
SCHEMBL5516763 0.67
SCHEMBL708104 0.64
SCHEMBL7574772 0.62
SCHEMBL30621360 0.62
SCHEMBL28952772 0.61
SCHEMBL28838315 0.61
SCHEMBL9637561 0.61
SCHEMBL68461 0.61
SCHEMBL3682865 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102574875-A Process for production of silane coupling agents BRIDGESTONE CORP 2012-07-11 CN claimed
CN-113735457-A Hydrophilic base material and method for producing hydrophilic base material 住友橡胶工业株式会社 2021-12-03 CN disclosed
EP-3121643-B1 OPHTHALMIC LENS MENICON CO LTD (JP) 2020-07-22 EP disclosed
EP-3086162-B1 OCULAR LENS MENICON CO LTD (JP) 2019-04-17 EP disclosed
EP-3086163-B1 POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME MENICON CO LTD (JP) 2018-11-14 EP disclosed
US-9770528-B2 Biomaterial compositions CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2017-09-26 US disclosed
US-9657131-B2 Ophthalmic lens MENICON CO., LTD. (JP) 2017-05-23 US disclosed
US-9650473-B2 Polysiloxane-based macromonomer for ophthalmic lens and ophthalmic lens using the same MENICON CO., LTD. (JP) 2017-05-16 US disclosed
EP-3121643-A1 OPHTHALMIC LENS Menicon Co., Ltd. (JP) 2017-01-25 EP disclosed
EP-3086162-A1 OCULAR LENS Menicon Co., Ltd. (JP) 2016-10-26 EP disclosed
EP-1378769-A2 Water-absorptive contact lens and method of producing the same Menicon Co., Ltd. (JP) 2004-01-07 EP disclosed
US-20030181506-A1 Selective preventives/remedies for progressive lesions after organ damage ISHIBASHI, MICHIO (JP) 2003-09-25 US disclosed
EP-1277747-A1 SELECTIVE PREVENTIVES/REMEDIES FOR PROGRESSIVE LESIONS AFTER ORGAN DAMAGE Ishibashi, Michio (JP) 2003-01-22 EP disclosed
EP-0872484-B1 ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2002-10-02 EP disclosed
US-6329027-B1 Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements CHISSO CORPORATION (JP) 2001-12-11 US disclosed
EP-1010692-A1 LIQUID-CRYSTAL COMPOUNDS HAVING LARGE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT MADE USING THE LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 2000-06-21 EP disclosed
US-6015843-A CURING; NONCYTOTOXIC; DENSITY SEPARATION GRADIENTS DENDREON CORPORATION (US) 2000-01-18 US disclosed
US-5993690-A Organosilicon compound, liquid crystal composition, and liquid-crystal display element CHISSO CORPORATION (JP) 1999-11-30 US disclosed
EP-0959060-A1 CHLOROBENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENTS CHISSO CORPORATION (JP) 1999-11-24 EP disclosed
EP-0872484-A1 ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-10-21 EP disclosed