SCHEMBL27308264

SCHEMBL27308264

CCCC[C@H](N)C(C)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 3/20 0.50
SLC1A1 P43005 3/20 0.50
SLC1A3 P43003 2/20 0.50
CA2 P00918 2/20 0.48
MAPK1 P28482 1/20 0.48
GRIK1 P39086 3/20 0.44
GRIK2 Q13002 3/20 0.44
SLC15A1 P46059 1/20 0.44
ACE2 Q9BYF1 1/20 0.42
GPR84 Q9NQS5 3/20 0.42
CA1 P00915 1/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.41
TP53 P04637 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
DPP7 Q9UHL4 2/20 0.41
DPP8 Q6V1X1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19198251 1.00 SLC1A2 (0.50) SLC1A2SLC1A1SLC1A3CA2MAPK1
SCHEMBL3216658 0.94 GRIK1 (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL3219925 0.94 GRIK1 (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL4936250 0.94 GRIK1 (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL25798403 0.94 GRIK1 (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL1162596 0.86 CHRM1 (0.48) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL804557 0.86 CHRM1 (0.48) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL27486931 0.84 SLC1A2 (0.49) SLC1A2SLC1A1SLC1A3CA2MAPK1
SCHEMBL27886717 0.81 GSR (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL31382811 0.81 GSR (0.52) SLC1A2SLC1A1SLC1A3GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073622-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2024-04-04 WO disclosed