Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500627 | 0.87 | TTR (0.55) | TTRMYCPOLBCSNK2A1METAP2 | |
| SCHEMBL27796585 | 0.78 | TTR (0.59) | TTRMYCPOLBCSNK2A1METAP2 | |
| SCHEMBL28759892 | 0.78 | TTR (0.59) | TTRMYCPOLBCSNK2A1METAP2 | |
| SCHEMBL28015624 | 0.78 | TTR (0.59) | TTRMYCNOTUMDHODH | |
| SCHEMBL27516459 | 0.78 | TTR (0.59) | TTRMYCMAPTALDH1A1NOTUM | |
| SCHEMBL27476636 | 0.78 | FFAR4 (0.53) | TTR | |
| SCHEMBL7843765 | 0.77 | FOLH1 (0.56) | MYCCLCN2MCL1ALDH1A1FOLH1 | |
| SCHEMBL27403003 | 0.76 | MYC (0.45) | TTRMYCCLCN2MAPTMCL1 | |
| SCHEMBL27532000 | 0.75 | TTR (0.56) | TTRMYCPOLBKDM4EMCL1 | |
| SCHEMBL27875963 | 0.75 | HTT (0.50) | MYCCLCN2MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628645-A | Pyrazole-containing bishydrazide compound and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-05-20 | — | — | CN | claimed |
| CN-104628645-B | Pyrazole-containing bishydrazide compound and preparation method and application thereof | 浙江工业大学 | 2017-01-25 | — | — | CN | disclosed |
| CN-104628645-A | Pyrazole-containing bishydrazide compound and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-05-20 | — | — | CN | disclosed |
| CN-1039645-C | 1,3-(substd. thio) acetoxy Melbamycinum derivatives, their preparation method, and use in agricultural chemistry | SANKYO CO (JP) | 1998-09-02 | — | — | CN | disclosed |
| CN-1074445-A | 13-(sulfo-of replacement) acetoxyl group milbemycin derivatives, their preparation and the application on the agrochemistry thereof | SANKYO CO (JP) | 1993-07-21 | — | — | CN | disclosed |