SCHEMBL27308331

SCHEMBL27308331

Brc1cc(Br)c2cc3cc(Br)cc(Br)c3cc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
PRNP P04156 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
NOD2 Q9HC29 1/20 0.35
AHR P35869 2/20 0.35
EGFR P00533 1/20 0.34
RXFP1 Q9HBX9 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
NQO2 P16083 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525331 0.88 CYP3A4 (0.39) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL31540581 0.85 CYP2A6 (0.50) TDP1CYP3A4TSHRNPSR1HPGD
SCHEMBL6754533 0.83 CYP2A6 (0.48) TDP1CYP3A4TSHRNPSR1HPGD
SCHEMBL28253602 0.80 CYP2A6 (0.44) TDP1CYP3A4TSHRLMNAHPGD
SCHEMBL8556469 0.78 CYP2A6 (0.48) TDP1CYP3A4TSHRLMNAHPGD
SCHEMBL30449010 0.76 TDP1 (0.50) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL4324429 0.76 TDP1 (0.50) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL21546553 0.73 CYP2A6 (0.33) TDP1CYP3A4TSHRRXFP1ALDH1A1
SCHEMBL29524488 0.73 CYP2A6 (0.48) TDP1CYP3A4TSHRHPGDRXFP1
SCHEMBL3103031 0.73 CYP2A6 (0.48) TDP1CYP3A4TSHRHPGDRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed