Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | WIZ | O95785 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305818 | 0.92 | CRBN (0.59) | CRBNESR1IKZF2WIZ | |
| SCHEMBL27308323 | 0.92 | CRBN (0.61) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL27310070 | 0.91 | CRBN (0.59) | CRBNESR1IKZF2WIZ | |
| Hydrochloric Acid SCHEMBL30906238 | 0.91 | CRBN (0.60) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL27302968 | 0.91 | CRBN (0.61) | CRBNESR1IKZF2WIZ | |
| SCHEMBL30906253 | 0.90 | CRBN (0.63) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL25079658 | 0.90 | CRBN (0.71) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL22600233 | 0.90 | CRBN (0.60) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL24735305 | 0.90 | CRBN (0.60) | CRBNESR1IKZF2IKZF1WIZ | |
| SCHEMBL29841272 | 0.90 | CRBN (0.60) | CRBNESR1IKZF2IKZF1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077244-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | HOTSPOT THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | WO | disclosed |