Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209519 | 0.89 | TDP1 (0.49) | MAPTIDO1PPARACA1CA2 | |
| SCHEMBL31307121 | 0.89 | IDO1 (0.48) | IDO1PPARACA1CA2CA12 | |
| SCHEMBL31307122 | 0.87 | IDO1 (0.47) | IDO1PPARACA1CA2CA12 | |
| SCHEMBL27306067 | 0.87 | IDO1 (0.47) | IDO1PPARACA1CA2CA12 | |
| SCHEMBL25301986 | 0.87 | IDO1 (0.47) | L3MBTL1IDO1PPARACA1CA2 | |
| SCHEMBL24812942 | 0.87 | IDO1 (0.47) | L3MBTL1IDO1PPARACA1CA2 | |
| SCHEMBL506649 | 0.87 | IDO1 (0.62) | MAPTL3MBTL1IDO1PPARACA1 | |
| SCHEMBL13185216 | 0.84 | CA12 (0.57) | MAPTL3MBTL1IDO1CA1CA2 | |
| SCHEMBL17974332 | 0.83 | CA12 (0.66) | MAPTL3MBTL1IDO1CA1CA2 | |
| SCHEMBL31307120 | 0.83 | IDO1 (0.44) | MAPTIDO1PPARACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077244-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | HOTSPOT THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | WO | disclosed |