Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 14/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922982 | 0.85 | TDP1 (0.60) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL9512370 | 0.84 | TDP1 (0.48) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL278504 | 0.83 | TDP1 (0.62) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL278949 | 0.82 | TDP1 (0.51) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL278628 | 0.81 | TDP1 (0.60) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL273405 | 0.81 | TDP1 (0.60) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL278621 | 0.81 | TDP1 (0.60) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1197124 | 0.80 | TDP1 (0.58) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL28187039 | 0.79 | TDP1 (0.47) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL20651994 | 0.78 | TSHR (0.44) | TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133996-B2 | Process for the preparation of ethyl-N-(2,3-dichloro-6-nitrobenzyl)glycine hydrochloride | CIPLA LIMITED (IN) | 2012-03-13 | — | — | US | disclosed |
| US-20100075999-A1 | Process for the Preparation of Ethyl-N-(2,3-Dichloro-6-Nitrobenzyl)Glycine Hydrochloride | CIPLA LIMITED (IN) | 2010-03-25 | — | — | US | disclosed |
| EP-2114856-A1 | PROCESS FOR THE PREPARATION OF ETHYL-N-(2, 3-DICHLORO-6-NITROBENZYL) GLYCINE HYDROCHLORIDE | Cipla Limited (IN) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008096145-A1 | PROCESS FOR THE PREPARATION OF ETHYL-N-(2, 3-DICHLORO-6-NITROBENZYL) GLYCINE HYDROCHLORIDE | CIPLA LIMITED (IN) | 2008-08-14 | — | — | WO | disclosed |
| EP-0175151-A1 | 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation | BAYER AG (DE) | 1986-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075999-A1 | Process for the Preparation of Ethyl-N-(2,3-Dichloro-6-Nitrobenzyl)Glycine Hydrochloride | CDK13, CBR3, SUCNR1 | TDP1 4495/4885TSHR 2160/4885MAPK1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.