Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 4/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27310506 | 0.93 | GLP1R (0.48) | GLP1RSIRT5TLR2ALB | |
| SCHEMBL27310385 | 0.84 | GLP1R (0.57) | GLP1RTLR2ALBROCK2PRKACA | |
| SCHEMBL12981270 | 0.82 | GLP1R (0.56) | GLP1RSIRT5TLR2SIRT6SIRT1 | |
| SCHEMBL14902999 | 0.82 | GLP1R (0.46) | GLP1RSIRT5TLR2ALBROCK2 | |
| SCHEMBL25454957 | 0.81 | GLP1R (0.46) | GLP1RSIRT5TLR2ALBROCK2 | |
| SCHEMBL13475034 | 0.81 | GLP1R (0.56) | GLP1RSIRT5TLR2ALBSIRT6 | |
| SCHEMBL21166939 | 0.81 | GLP1R (0.55) | GLP1RSIRT5TLR2SIRT6SIRT1 | |
| SCHEMBL26425890 | 0.80 | GLP1R (0.48) | GLP1RTLR2ALBCCKARCCKBR | |
| SCHEMBL27310507 | 0.80 | GLP1R (0.44) | GLP1RSIRT5TLR2ALBCCKAR | |
| SCHEMBL8116615 | 0.79 | GLP1R (0.58) | GLP1RTLR2SIRT6SIRT1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073622-A2 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF | RAYZEBIO, INC. (US) | 2024-04-04 | — | — | WO | disclosed |