Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 7/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381594 | 1.00 | CES1 (0.62) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL1588346 | 0.92 | CES1 (0.58) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL29539040 | 0.92 | CES1 (0.58) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL4737998 | 0.84 | CES1 (0.71) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL29758482 | 0.84 | CES1 (0.57) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL1589486 | 0.84 | CES1 (0.57) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL17221433 | 0.77 | GRM5 (0.43) | CES1BCHETGM2ALDH1A1ALDH2 | |
| SCHEMBL1085000 | 0.77 | CES1 (0.58) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL5526009 | 0.77 | CES1 (1.00) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL18256571 | 0.77 | CES1 (0.71) | CES1BCHETGM2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006242-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2018-01-04 | — | — | US | disclosed |
| US-20160016952-A1 | SUBSTITUTED AMINO-PYRIMIDINE DERIVATIVES | ASANA BIOSCIENCES, LLC (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160016952-A1 | SUBSTITUTED AMINO-PYRIMIDINE DERIVATIVES | ASANA BIOSCIENCES, LLC (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160016952-A1 | SUBSTITUTED AMINO-PYRIMIDINE DERIVATIVES | ASANA BIOSCIENCES, LLC (US) | 2016-01-21 | — | — | US | disclosed |
| US-9145411-B2 | Substituted amino-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145411-B2 | Substituted amino-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145411-B2 | Substituted amino-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-09-29 | — | — | US | disclosed |
| US-9115092-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-9115092-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-9115092-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ASANA BIOSCIENCES, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20130190492-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190492-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-8440662-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ENDO PHARMACEUTICALS, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440662-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ENDO PHARMACEUTICALS, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440662-B2 | Substituted quinazoline and pyrido-pyrimidine derivatives | ENDO PHARMACEUTICALS, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-20120129851-A1 | Substituted Quinazoline and Pyrido-Pyrimidine Derivatives | ENDO PHARMACEUTICALS INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129851-A1 | Substituted Quinazoline and Pyrido-Pyrimidine Derivatives | ENDO PHARMACEUTICALS INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129851-A1 | Substituted Quinazoline and Pyrido-Pyrimidine Derivatives | ENDO PHARMACEUTICALS INC. (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2012058671-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012058671-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016952-A1 | SUBSTITUTED AMINO-PYRIMIDINE DERIVATIVES | MTOR, PIK3CA, AKT3 | CES1 3643/4885BCHE 3547/4885TGM2 4262/4885 |
| US-20130190492-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | MTOR, PIK3CA, PDPK1 | CES1 4118/4885BCHE 3861/4885TGM2 4464/4885 |
| US-20180006242-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY DEVICE | OR10J3, ODC1, OR51E2 | CES1 3625/4885BCHE 1808/4885TGM2 2948/4885 |
| US-20120129851-A1 | Substituted Quinazoline and Pyrido-Pyrimidine Derivatives | MTOR, PIK3CA, PDPK1 | CES1 4118/4885BCHE 3861/4885TGM2 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.