Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.66 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.66 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.66 |
| ▸ | OXTR | P30559 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712149 | 0.91 | AVPR1A (0.70) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8713010 | 0.85 | AVPR1A (0.70) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8715943 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8712963 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8718080 | 0.83 | AVPR1A (0.73) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL27323365 | 0.83 | PTGDR2 (0.55) | PTGDR2 | |
| SCHEMBL8712791 | 0.83 | AVPR1A (0.67) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8715795 | 0.82 | AVPR1A (0.71) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8712361 | 0.81 | AVPR1A (0.70) | AVPR1AAVPR2AVPR1BOXTRABCB11 | |
| SCHEMBL8714659 | 0.81 | AVPR1A (0.57) | AVPR1AAVPR2AVPR1BOXTRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048484-C | A process for preparing a composition containing benzoheterocycles | OTSUKA PHARMA CO LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1027505-C | Process for preparing benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | CN | disclosed |