Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 4/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315070 | 0.81 | POLB (0.42) | POLBRAB9ANPC1NR3C2KDM4E | |
| SCHEMBL6071072 | 0.78 | DYRK1A (0.41) | POLBRAB9ANPC1NR3C2DYRK1A | |
| SCHEMBL19924519 | 0.78 | PDE10A (0.44) | POLBNR3C2ALDH1A1MAPK9MAPK13 | |
| SCHEMBL6070872 | 0.76 | MDM2 (0.40) | POLBRAB9ANR3C2DYRK1AHTT | |
| SCHEMBL7256639 | 0.76 | MDM2 (0.38) | POLBNR3C2KDM4EALDH1A1MAPK9 | |
| SCHEMBL27309749 | 0.74 | MAPK9 (0.48) | HSP90AA1POLBNR3C2KDM4EALDH1A1 | |
| SCHEMBL27353154 | 0.74 | POLB (0.53) | POLBRAB9ANPC1NR3C2KDM4E | |
| SCHEMBL15452435 | 0.74 | GRM4 (0.54) | HSP90AA1AURKAPRKACAADORA2ARAB9A | |
| SCHEMBL16877063 | 0.73 | HSP90AA1 (0.46) | HSP90AA1AURKAPRKACAADORA2ARAB9A | |
| SCHEMBL6070069 | 0.71 | CDK2 (0.53) | DYRK1APTK2GSK3BCDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031570-C | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-04-17 | — | — | CN | disclosed |
| CN-1044656-A | Pyrazolopyridine compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-08-15 | — | — | CN | disclosed |