Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25972897 | 0.77 | PLAU (0.42) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL18525734 | 0.77 | HTT (0.43) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL10170376 | 0.77 | KMT2A (0.56) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL24007348 | 0.77 | PLAU (0.38) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL12238975 | 0.77 | HTT (0.37) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL24446510 | 0.77 | HTT (0.37) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL10170378 | 0.77 | HTT (0.39) | PLAUHTTKMT2AMEN1POLB | |
| SCHEMBL10297745 | 0.72 | HTT (0.34) | HTTKMT2AMEN1POLBMAPT | |
| SCHEMBL16303844 | 0.70 | MEN1 (0.36) | HTTKMT2AMEN1POLBMAPT | |
| SCHEMBL28145715 | 0.70 | SMN1; SMN2 (0.45) | HTTKMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038357-A1 | SYNTHESIS OF SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS AND ANALOGUES THEREOF | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-02-22 | — | — | WO | disclosed |