Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 17/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133193 | 0.88 | HCRTR2 (0.80) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2133545 | 0.76 | HCRTR2 (0.82) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2131261 | 0.74 | HCRTR2 (1.00) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2131153 | 0.73 | HCRTR2 (1.00) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2131642 | 0.72 | HCRTR2 (0.76) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2130979 | 0.71 | HCRTR2 (0.83) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2138774 | 0.70 | HCRTR2 (0.85) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2131913 | 0.69 | HCRTR2 (0.72) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2131712 | 0.69 | HCRTR2 (0.79) | HCRTR2HCRTR1HTR1ATSPO | |
| SCHEMBL2733526 | 0.69 | HCRTR2 (0.63) | HCRTR2HCRTR1HTR1ATSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632924-A1 | DIAZA-SPIRO[5.5]UNDECANES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2013-09-04 | — | — | EP | claimed |
| WO-2012055888-A1 | DIAZA-SPIRO[5.5]UNDECANES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2012-05-03 | — | — | WO | claimed |