SCHEMBL27314

SCHEMBL27314

[CH2]OCC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433951 0.74
SCHEMBL813821 0.67
SCHEMBL787874 0.67
SCHEMBL290983 0.65
SCHEMBL1148834 0.65
SCHEMBL15359393 0.64
SCHEMBL10979113 0.62
SCHEMBL23302398 0.61
SCHEMBL4691298 0.61
SCHEMBL2889249 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6995 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024093907-A1 LIGAND FOR DELIVERING SIRNA TO EYE AND CENTRAL NERVOUS SYSTEM 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
WO-2024093947-A1 PRODRUG FOR DELIVERING SIRNA INTO CELL 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
US-10870651-B2 Inhibitors of cyclin-dependent kinase 7 (CDK7) DANA-FARBER CANCER INSTITUTE, INC. (US) 2020-12-22 US claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
EP-0545912-A2 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1993-06-09 EP claimed
WO-1993006079-A1 PREPARATION OF SUBSTITUTED ISOSERINE ESTERS USING METAL ALKOXIDES AND β-LACTAMS FLORIDA STATE UNIVERSITY (US) 1993-04-01 WO claimed
WO-1993006094-A1 METAL ALKOXIDES FLORIDA STATE UNIVERSITY (US) 1993-04-01 WO claimed
US-5175315-A Reacting with alcohol in presence of altivating agent FLORIDA STATE UNIVERSITY (US) 1992-12-29 US claimed
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 EP claimed
US-5136060-A Reacting with alcohol FLORIDA STATE UNIVERSITY (US) 1992-08-04 US claimed
US-5126267-A Protected hydroxy method for alcohol-ester separation EASTMAN KODAK COMPANY (US) 1992-06-30 US claimed
EP-0428376-A1 Method for preparation of taxol using an oxazinone FLORIDA STATE UNIVERSITY (US) 1991-05-22 EP claimed
US-5015744-A Esterification of an alcohol with an oxazinone FLORIDA STATE UNIVERSITY (US) 1991-05-14 US claimed
EP-0400971-A2 Method for preparation of taxol FLORIDA STATE UNIVERSITY (US) 1990-12-05 EP claimed