SCHEMBL27314034

SCHEMBL27314034

Cn1cnnc1-c1cnn(C)c1-c1cc(NCC2CCC2)nc(N2Cc3c(cccc3C(F)(F)F)C2=O)c1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27313883 0.97 CBLB (0.64) CBLB
SCHEMBL27316383 0.91 CBLB (0.63) CBLB
SCHEMBL29920616 0.90 CBLB (0.68) CBLB
SCHEMBL27086284 0.90 CBLB (0.68) CBLB
SCHEMBL27291967 0.90 CBLB (0.65) CBLB
SCHEMBL27287876 0.89 CBLB (0.66) CBLB
SCHEMBL27316038 0.88 CBLB (0.65) CBLB
SCHEMBL27292175 0.88 CBLB (0.66) CBLB
SCHEMBL27290351 0.88 CBLB (0.64) CBLB
SCHEMBL29920672 0.87 CBLB (0.68) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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