Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394822 | 0.92 | RET (0.57) | RET | |
| SCHEMBL27315094 | 0.87 | RET (0.46) | RET | |
| SCHEMBL30906951 | 0.85 | RET (0.41) | RET | |
| SCHEMBL27315152 | 0.84 | RET (0.57) | RET | |
| SCHEMBL30906950 | 0.80 | RET (0.56) | RET | |
| SCHEMBL27315162 | 0.80 | RET (0.56) | RET | |
| SCHEMBL27315613 | 0.80 | RET (0.50) | RET | |
| SCHEMBL27315191 | 0.77 | RET (0.51) | RET | |
| SCHEMBL27315219 | 0.75 | RET (0.54) | RET | |
| SCHEMBL27315615 | 0.71 | NTRK1 (0.58) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611900-A1 | RET-LDD PROTEIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-4611901-A1 | RET-LDD PROTEIN DEGRADERS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097980-A1 | RET-LDD PROTEIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097989-A1 | RET-LDD PROTEIN DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |