Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269578 | 0.97 | — | — | |
| SCHEMBL215572 | 0.97 | — | — | |
| SCHEMBL769926 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4269574 | 0.94 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL406007 | 0.94 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL215571 | 0.94 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3926493 | 0.92 | TSHR (0.43) | TSHRHCAR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL21612233 | 0.92 | TSHR (0.43) | TSHRHCAR2CA12CA1CA2 | |
| Sulfuric Acid SCHEMBL31066598 | 0.87 | TSHR (0.40) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL19123628 | 0.87 | TSHR (0.40) | TSHRHCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034016-C | Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids | ACRAF (IT) | 1997-02-12 | — | — | CN | claimed |
| CN-1088201-A | The method for making of 1-benzyl-3-methylol-indazole | ACRAF (IT) | 1994-06-22 | — | — | CN | claimed |
| CN-1044810-A | Ethers of 1-benzyl-3-hydroxymethyl-indazole and aliphatic-2-hydroxy acids | ACRAF (IT) | 1990-08-22 | — | — | CN | claimed |
| CN-1046505-C | Process for the preparation of ethers of 1-benzyl-3-hydroxymethyl-indazole and aliphatic 2-hydroxy acids | ACRAF (IT) | 1999-11-17 | — | — | CN | disclosed |
| CN-1034016-C | Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids | ACRAF (IT) | 1997-02-12 | — | — | CN | disclosed |
| CN-1088201-A | The method for making of 1-benzyl-3-methylol-indazole | ACRAF (IT) | 1994-06-22 | — | — | CN | disclosed |
| CN-1044810-A | Ethers of 1-benzyl-3-hydroxymethyl-indazole and aliphatic-2-hydroxy acids | ACRAF (IT) | 1990-08-22 | — | — | CN | disclosed |