⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959524 | 0.77 | — | — | |
| SCHEMBL1566842 | 0.77 | — | — | |
| SCHEMBL26635455 | 0.71 | — | — | |
| Hydrogen Peroxide SCHEMBL28110842 | 0.68 | — | — | |
| SCHEMBL45145 | 0.68 | — | — | |
| SCHEMBL33633 | 0.68 | — | — | |
| SCHEMBL3675458 | 0.67 | — | — | |
| SCHEMBL4804969 | 0.67 | — | — | |
| SCHEMBL3104039 | 0.67 | — | — | |
| SCHEMBL15599670 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237549-A | Synthetic method for sirolimus 40-ether derivative | ZHEJIANG MED XINCHANG PHARM | 2016-01-13 | — | — | CN | claimed |
| CN-103554088-B | benzodiazepine compound and pharmaceutical composition | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2016-02-24 | — | — | CN | disclosed |
| CN-105237549-A | Synthetic method for sirolimus 40-ether derivative | ZHEJIANG MED XINCHANG PHARM | 2016-01-13 | — | — | CN | disclosed |
| CN-104507923-A | Substituted pyrrole active agents as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2015-04-08 | — | — | CN | disclosed |
| CN-104203946-A | Immunologically useful arginine salts | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| CN-103819314-A | Preparation method for acyclic compound used as foaming agent | ZHANG WEI | 2014-05-28 | — | — | CN | disclosed |
| CN-103554088-A | Benzodiazepine compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2014-02-05 | — | — | CN | disclosed |
| CN-101952259-B | Benzodiazepine compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-102329267-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-25 | — | — | CN | disclosed |
| CN-102311387-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-11 | — | — | CN | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| CN-1681804-A | Sulphonamide derivatives and their use as TACE inhibitors | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| CN-1136192-C | Aryl and heteroaryl sulfonamide derivatives, their preparation and their use as endothelin antagonists | - | 2004-01-28 | — | — | CN | disclosed |
| CN-1067988-C | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICS K K (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1051301-C | Indoloylguanidine derivatives | SUMITOMO PHARMA (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |
| CN-1170405-A | Aryl and heteroaryl sulfonamide derivatives, their preparation and their use as endothelin antagonists | HOFFMANN LA ROCHE (CH) | 1998-01-14 | — | — | CN | disclosed |
| CN-1136038-A | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICS K K (JP) | 1996-11-20 | — | — | CN | disclosed |
| CN-1106800-A | Indoloylguanidine derivatives | SUMITOMO PHARMA (JP) | 1995-08-16 | — | — | CN | disclosed |