Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316509 | 0.93 | CRBN (0.54) | CRBNGSPT1DDB1IKZF3IKZF1 | |
| SCHEMBL27316089 | 0.93 | CRBN (0.56) | CRBNGSPT1DDB1IKZF3IKZF1 | |
| SCHEMBL27317443 | 0.90 | CRBN (0.52) | CRBNGSPT1DDB1IKZF3IKZF1 | |
| SCHEMBL27317316 | 0.89 | CRBN (0.52) | CRBNIKZF1IKZF2 | |
| SCHEMBL27316411 | 0.89 | CRBN (0.53) | CRBNGSPT1DDB1IKZF3IKZF1 | |
| SCHEMBL27315986 | 0.88 | CRBN (0.56) | CRBNIKZF1IKZF2 | |
| SCHEMBL27316093 | 0.88 | CRBN (0.50) | CRBNIKZF1IKZF2 | |
| SCHEMBL27317074 | 0.88 | CRBN (0.54) | CRBNIKZF1IKZF2 | |
| SCHEMBL27316286 | 0.88 | CRBN (0.56) | CRBNIKZF1IKZF2 | |
| SCHEMBL27317139 | 0.88 | CRBN (0.53) | CRBNIKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054832-A1 | CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |