SCHEMBL27316632

SCHEMBL27316632

B.CCC1CCOC1(CC)CC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493775 0.98 KDM4E (0.32) KDM4EMAPTAPOBEC3G
SCHEMBL27401600 0.83
SCHEMBL24816239 0.71
SCHEMBL9129495 0.67 KDM4E (0.30) KDM4EMAPTAPOBEC3G
SCHEMBL27705452 0.65 KDM4E (0.33) KDM4EMAPTAPOBEC3G
SCHEMBL15013069 0.65 KDM4E (0.33) KDM4EMAPTAPOBEC3G
SCHEMBL15660472 0.64
SCHEMBL24916707 0.63 GAA (0.33) KDM4EMAPTAPOBEC3G
SCHEMBL27115715 0.60
SCHEMBL27115714 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279227-A The preparation method of lithium triethylborohydride tetrahydrofuran solution 车荣睿 2017-01-04 CN claimed
CN-109517158-A A method of causing system without metal catalytic based on three components and prepares polyethers 华南理工大学 2019-03-26 CN disclosed
CN-105315320-B A kind of method preparing shellfish cholic acid difficult to understand 山东省药学科学院 2017-03-08 CN disclosed
CN-106279227-A The preparation method of lithium triethylborohydride tetrahydrofuran solution 车荣睿 2017-01-04 CN disclosed
CN-106279227-A The preparation method of lithium triethylborohydride tetrahydrofuran solution 车荣睿 2017-01-04 CN disclosed
CN-104334524-B The prodrug of fluorinated amino acids 大正制药株式会社 2016-10-12 CN disclosed
CN-104334524-A Prodrug of fluorine-containing amino acid TAISHO PHARMACEUTICAL CO LTD 2015-02-04 CN disclosed
CN-1034716-A Disubstituted pyridines and preparation method thereof BAYER AG (DE) 1989-08-16 CN disclosed