Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 18/20 | 0.58 |
| ▸ | XIAP | P98170 | 16/20 | 0.58 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728740 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL2731929 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL12568679 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL2731495 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL2731493 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL18494147 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL19309145 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL20231032 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL20334443 | 1.00 | BIRC2 (0.58) | BIRC2XIAPBIRC3 | |
| SCHEMBL10127375 | 0.99 | BIRC2 (0.59) | BIRC2XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052758-A1 | RESPONSE BIOMARKERS FOR IAP ANTAGONISTS IN HUMAN CANCERS | ASTRAZENECA AB (SE) | 2012-04-26 | — | — | WO | disclosed |