Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632968 | 0.84 | NISCH (0.47) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL6683975 | 0.79 | NISCH (0.43) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL6679046 | 0.77 | NISCH (0.42) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL8602132 | 0.77 | NISCH (0.42) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL19003445 | 0.77 | NISCH (0.42) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL268860 | 0.76 | NISCH (0.44) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL25487654 | 0.74 | NISCH (0.40) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL8601500 | 0.74 | NISCH (0.40) | NISCHADRB2ADRB1AOC3HIF1A | |
| SCHEMBL6527704 | 0.74 | NISCH (0.40) | NISCHADRB2ADRB1AOC3HIF1A | |
| Dimethylamine SCHEMBL10508428 | 0.73 | NISCH (0.50) | NISCHADRB2ADRB1AOC3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051311-C | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1100417-A | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |