SCHEMBL27320102

SCHEMBL27320102

CCC(O)COC(O)CC

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489135 0.92 TSHR (0.50) TSHRKDM4E
SCHEMBL888322 0.84 TSHR (0.43) TSHRKDM4E
SCHEMBL27933045 0.79 TSHR (0.39) TSHR
SCHEMBL16172597 0.78
SCHEMBL296902 0.78
SCHEMBL6144674 0.78
SCHEMBL16172598 0.78
SCHEMBL3626082 0.78
SCHEMBL14004726 0.78
SCHEMBL13500024 0.78 TSHR (0.35) TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102718766-B Method for preparing diacetylacyclovir with 7-bit diacetylacyclovir UNIV ZHEJIANG TECHNOLOGY 2014-09-03 CN claimed
CN-109134174-A It is a kind of for toluene/aceticanhydride/2- oxa- -1,4- diethyl-butanediol separation method and equipment 天津中福泰克化工科技有限公司 2019-01-04 CN disclosed
CN-109134174-A It is a kind of for toluene/aceticanhydride/2- oxa- -1,4- diethyl-butanediol separation method and equipment 天津中福泰克化工科技有限公司 2019-01-04 CN disclosed
CN-109134174-A It is a kind of for toluene/aceticanhydride/2- oxa- -1,4- diethyl-butanediol separation method and equipment 天津中福泰克化工科技有限公司 2019-01-04 CN disclosed
CN-102718766-B Method for preparing diacetylacyclovir with 7-bit diacetylacyclovir UNIV ZHEJIANG TECHNOLOGY 2014-09-03 CN disclosed
CN-102718767-B Method for synthesizing diacetylacyclovir UNIV ZHEJIANG TECHNOLOGY 2014-09-03 CN disclosed
CN-102718766-A Method for preparing diacetylacyclovir with 7-bit diacetylacyclovir UNIV ZHEJIANG TECHNOLOGY 2012-10-10 CN disclosed
CN-1137892-C Preparation of N-9 substituted guanine compound - 2004-02-11 CN disclosed
CN-1051084-C Preparation of N-9 substituted guanine compounds HOFFMANN LA ROCHE (CH) 2000-04-05 CN disclosed
CN-1246477-A Preparation of N-9 substituted guanine compound HOFFMANN LA ROCHE (CH) 2000-03-08 CN disclosed
CN-1120044-A Preparation of N-9 substituted guanine compounds HOFFMANN LA ROCHE (US) 1996-04-10 CN disclosed