SCHEMBL2732037

SCHEMBL2732037

C=CCN(N=O)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 2/20 0.59
CNR2 P34972 2/20 0.49
CNR1 P21554 1/20 0.49
TDP1 Q9NUW8 1/20 0.44
ATM Q13315 1/20 0.44
MAPT P10636 1/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
GLA P06280 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
AGER Q15109 1/20 0.41
GAA P10253 2/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
TLR9 Q9NR96 1/20 0.40
ESR1 P03372 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258729 0.81 C5AR1 (0.64) C5AR1CNR2CNR1TDP1MAPT
SCHEMBL29268400 0.80 CA1 (0.47) C5AR1TDP1ATMMAPTCA12
SCHEMBL12169302 0.79 C5AR1 (0.62) C5AR1CNR2CNR1TDP1ATM
SCHEMBL2722526 0.79 MAPT (0.48) C5AR1CNR2CNR1ATMMAPT
SCHEMBL1181090 0.78 C5AR1 (0.60) C5AR1CNR2CNR1TDP1ATM
SCHEMBL17352312 0.78 C5AR1 (0.60) C5AR1CNR2CNR1TDP1ATM
SCHEMBL5615162 0.78 C5AR1 (0.60) C5AR1CNR2CNR1TDP1ATM
SCHEMBL15898561 0.77 CNR2 (0.67) C5AR1CNR2CNR1TDP1GLA
SCHEMBL29144994 0.76 MAPT (0.46) C5AR1CNR2ATMMAPTMCOLN3
SCHEMBL31729682 0.75 C5AR1 (0.57) C5AR1CNR2CNR1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US claimed
US-9249088-B2 Continuous production and reaction of a diazo compound DPX HOLDINGS B.V. (NL) 2016-02-02 US disclosed
EP-2635548-B1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DPX HOLDINGS BV (NL) 2014-12-17 EP disclosed
US-20140100360-A1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) 2014-04-10 US disclosed
EP-2635548-A2 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM IP Assets B.V. (NL) 2013-09-11 EP disclosed
WO-2012059485-A2 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM IP ASSETS B.V. (NL) 2012-05-10 WO disclosed
US-7902342-B2 Method for producing gaseous diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2011-03-08 US disclosed
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US disclosed