Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 20/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 20/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 20/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 20/20 | 0.55 |
| ▸ | USP2 | O75604 | 16/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 15/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 15/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867148 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL30867158 | 0.90 | GAA (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL27319925 | 0.90 | GAA (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL27319999 | 0.88 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL30867134 | 0.88 | HPGD (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL30867208 | 0.88 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL27320856 | 0.88 | HPGD (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL30867136 | 0.87 | NQO1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL27318685 | 0.87 | NQO1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL30867199 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |