Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17764795 | 1.00 | TDP1 (0.76) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL29391643 | 0.90 | TDP1 (0.76) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL164208 | 0.90 | TDP1 (0.76) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL29413979 | 0.86 | TDP1 (1.00) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL11790898 | 0.86 | TDP1 (0.71) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL14906 | 0.86 | TDP1 (1.00) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL11651820 | 0.85 | TDP1 (0.77) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| Hydrogen Sulfide SCHEMBL28307249 | 0.85 | TDP1 (0.98) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL27479445 | 0.85 | TDP1 (0.69) | TDP1ALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL9420507 | 0.85 | TDP1 (0.69) | TDP1ALDH1A1GPR35KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046706-C | Phenylacetic acid derivatives, their preparation and related intermediates, and compositions containing them | BASF AG (DE) | 1999-11-24 | — | — | CN | disclosed |