Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
| ▸ | WIZ | O95785 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316501 | 0.90 | CRBN (0.57) | CRBNIKZF2IKZF1 | |
| SCHEMBL27317221 | 0.89 | CRBN (0.49) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27322113 | 0.87 | CRBN (0.55) | CRBNIKZF2IKZF1 | |
| SCHEMBL27324613 | 0.86 | IKZF2 (0.48) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27311175 | 0.86 | CRBN (0.54) | CRBNIKZF2IKZF1 | |
| SCHEMBL27316093 | 0.86 | CRBN (0.50) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27315982 | 0.85 | IKZF2 (0.55) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27317316 | 0.85 | CRBN (0.52) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27311179 | 0.85 | CRBN (0.54) | CRBNIKZF2IKZF1 | |
| SCHEMBL27322320 | 0.84 | CRBN (0.56) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054832-A1 | CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |