Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309802 | 0.90 | CRBN (0.43) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL27309787 | 0.90 | CRBN (0.43) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL26188534 | 0.90 | CRBN (0.43) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL30822470 | 0.86 | CRBN (0.42) | CRBNDDB1PARP1PARP10MEN1 | |
| SCHEMBL31125231 | 0.83 | CRBN (0.42) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL845542 | 0.83 | CRBN (0.51) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL20128632 | 0.83 | CRBN (0.51) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL20128631 | 0.83 | CRBN (0.51) | CRBNDDB1HTR2AHTR2CHTR2B | |
| SCHEMBL23250094 | 0.80 | CRBN (0.50) | CRBNDDB1HTR2BCYP3A4 | |
| SCHEMBL26375163 | 0.80 | SRD5A1 (0.39) | CRBNDDB1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030968-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2024-02-08 | — | — | WO | disclosed |